Main areas of research:

Neuroimmunology (multiple sclerosis and Experimental Autoimmune Encephalomyelitis), Stem cells (EPC) and Extracorporeal Photochemotherapy

Interests/keywords:

EAE, neutrophils, immune regulation, immunosuppressive therapy, neuropathy, neurotoxicity and neuroprotection

flow cytometry, cell cyle + cell death detection and mechanisms,

Current title/position:

Post PhD

Current affiliation/employer:

Università di Milano-Bicocca, Dept. Neuroscience and Biomedical Technologies

PhD Advisor and University:

Dr G. Tredici, Università di Mialno-Bicocca

Postdoc Advisor and University:

Dr. G. Cavaletti, Università di Milano-Bicocca

Personal or laboratory homepage:

http://dntb.medicina.unimib.it/cmsDNTB/home.html

Publications:

Rigolio R., Biffi A., Oggioni N., Cavaletti G., 2008 Actively induced EAE in Lewis rats: characterization of spleen and spinal cord infiltrating lymphocytes by flow cytometry during the course of the disease. Journal of Neuroimmunology 199, 67–74.

Biffi A, Cavaletti G., Rigolio R. 2008 La citofluorimetria a flusso nella caratterizzazione immunofenotipica dei linfociti in corso di Encefalite Autoimmune Sperimentale. Invited article Lettere GIC 17 (3), 17-21.

Crimi M., Rigolio R., 2008. The mitochondrila genome, a growing interest inside an organelle. Interantional Journal of Nanomedicine 3:51–57.

Rigolio R., Perseghin P., Jonsson S., Petersson J., Cavaletti G., Cilio C.M.,. 2007. A new device to study ex-vivo the effects of extracorporeal photochemotherapy on the immune system. Journal of Photochemistry and Photobiology B: Biology. 88, 68-75.

Rigolio R., Miloso M., Nicolini G., Villa D., Scuteri A.., Simone M., Tredici G., 2005. Resveratrol interference with the cell cycle protects human neuroblastoma SH-SY5Y cell from paclitaxel-induced apoptosis. Neurochemistry International. 46, 205 – 211.

Nicolini G., Rigolio R., Miloso M., Bertelli A.A.E, Tredici G., 2001. Anti-apoptotic effect of trans-resveratrol on Paclitaxel-induced apoptosis in the human neuroblastoma SH-SYSY cell line. Neuroscience Letters 302, 41-44.


Chiorazzi A., Nicolini G., Canta A., Oggioni N., Rigolio R., Cossa G., Lombardi R., Roglio I., Cervellini I., Lauria G., Melcangi R.C., Bianchi R., Crippa D., Cavaletti G. 2009 Experimental Epothilone B neurotoxicity: results of in vitro and in vivo studies. Neurobiol Dis. 35(2), 270 - 7

Marmiroli P., Rodriguez-Menendez V., Rigamonti L., Tonoli E., Rigolio R., Guido G., Tredici G.,Vercelli A. 2009 Neuropathological changes in the peripheral nervous system and spinal cord in a transgenic mouse model of Niemann-Pick disease type A. Clinical Neurophatology 28 (4), 263 - 274

Villa D., Miloso M., Nicolini G., Rigolio R., Villa A., Cavaletti G., Tredici G., 2005. Low-dose cisplatin protects human neuroblastoma SH-SY5Y cells from paclitaxel-induced apoptosis. Molecular Cancer Therapeutics. 4, 1439- 1447.

Cavaletti G., Cavalletti E., Crippa L., Di Luccio E., Oggioni N., Mazzanti B., Biagioli T., Sala F., Sala V., Frigo M., Rota S., Tagliabue E., Stanzani L., Galbiati S., Rigolio R., Zoia C., Tredici G., Perseghin P., Dassi M., Riccio P., Lolli F., 2004. Pixantrone (BBR2778) reduces the severity of experimental allergic encephalomyelitis. Journal of Neuroimmunology 151, 55-65.

Nicolini G., Rigolio R., Scuteri A., Miloso M., Saccomannno D., Cavaletti G., Tredici G., 2003. Effect of trans-resveratrol on signal transduction pathways involved in paclitaxel-induced apoptosis in human neuroblastoma SH-SY5Y cells. Neurochemistry International 42, 419-29.

Cavaletti G., Petruccioli M.G., Marmiroli P., Rigolio R., Galbiati S., Zoia C., Ferrarese C., Tagliabue E., Dolci C., Bayssas M., Griffon Etienne G., Tredici G., 2002. Circulating nerve growth factor level changes during oxaliplatin treatment-induced neurotoxicity in the rat. Anticancer Research 22, 4199-4204.