Dear Ms Robin,
Microglia do phagocytic functions in brain. I was wondering if at the time of glioma surgery we take small piece of normal brain and isolate microglial cells and then grow them in lab , we could use them in same patient by delivering through intra-arterial route by selective microcatheter in tumour bed, some gliomas might reduce in size. Alternatively NK lymhocytes from same patient could be grown in lab and similarily injected. These cells can be tagged with radioactive substance to identify their final place and can be delivered by image guided system inside tumour.
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Microglia do phagocytic functions in brain. I was wondering if at the time of glioma surgery we take small piece of normal brain and isolate microglial cells and then grow them in lab , we could use them in same patient by delivering through intra-arterial route by selective microcatheter in tumour bed, some gliomas might reduce in size. Alternatively NK lymhocytes from same patient could be grown in lab and similarily injected. These cells can be tagged with radioactive substance to identify their final place and can be delivered by image guided system inside tumour.