According to recent research, the following drugs of abuse studied that may cause effects on synaptic transmission are:

Alcohol  

Alcohol inhibits neurotransmission in two ways. First, it inhibits the excitatory channels on the postsynaptic neuron. Next, it lowers the rate of action potentials from the presynaptic neuron.  

Caffeine  

At synapses where adenosine is the primary neurotransmitter, a high…