Mike Pascoe's Blog (20)

Hot off the Press - Week of May 10

Papers that entered my library during the Week of May 10:

Elbasiouny et al. Persistent inward currents in spinal motoneurons: Important for normal function but potentially harmful after spinal cord injury and in amyotrophic lateral sclerosis. Clinical neurophysiology (2010)

Engelhardt et al.…

Added by Mike Pascoe on May 14, 2010 at 5:00pm — No Comments

Hot off the Press - Week of May 3

It just dawned on me this morning that I add a lot of literature to my library of PDFs in a given week.

Often, I have colleagues sending me "new" papers that I already have in my library. So I figured it might be a good exercise for myself and others in my field to review the papers I have uncovered and if time permits, give some comments on why the papers were interesting enough to make it into my…

Added by Mike Pascoe on May 7, 2010 at 5:00pm — No Comments

Up close and personal with a fine wire electrode.

Essentially, the technique employed by neurophysiologists to recorded motor unit activity has remained unchanged since the 1920s.

A fine wire is placed in a hypodermic needle, which is placed inside the skeletal muscle of the volunteer (Fig. 13 from Adrian & Bronk, 1929, J Physiol). The small size of the fine wire offers a small recording volume, which is necessary to isolate the muscle…

Added by Mike Pascoe on May 4, 2010 at 3:55pm — No Comments

Decoding forearm EMG signals to control electronic devices

Microsoft Research has recently applied for a patent to develop a new way we interact with electronic devices. Typically, the mechanical force we exert on objects (e.g., using a keyboard) has been the interaction of choice to control electronic devices. This emerging technology uses the electric activity of muscles detected by electrodes on the skin.… Continue

Added by Mike Pascoe on January 7, 2010 at 12:24pm — No Comments

Doctor Yeti Weighs in on the Slicing of H.M.'s Brain

The slicing of H.M.'s brain has come to pass. What a great way to share neuroscience with the world!

Almost everyone I told about this event was super interested, including my family and non-academic friends.

But still, I couldn't help but wonder what local advice columnist *slash* mythical creature Doctor Yeti (pictured below) had to say about the momentous… Continue

Added by Mike Pascoe on December 7, 2009 at 6:00pm — No Comments

Exploring H.M.'s brain, one 70 micron slice at a time

Something historic in neuroscience is happening right now. Researchers are slicing the brain of the most famous amnesic patient "H. M." live and viewable through a webcam.

A detailed description can be found at the Sign On San Diego… Continue

Added by Mike Pascoe on December 3, 2009 at 2:08pm — No Comments

Artifacts from Neuroscience

Click on the photo below to be directed to flickr and to read more about each object pictured.

SfN Chicago 2009

Added by Mike Pascoe on November 16, 2009 at 4:39pm — No Comments

Steadiness in Stroke & Classifying Spasms

Tuesday morning was one of those blocks of time where I actually had very little going on and only a couple of posters to visit. The posters I did visit brought me from my dissertation question of how the nervous system changes with age to the question of what happens with neurological disorders.

Control of constant low-level isometric force after stroke- #568.20

Dr. McNulty's study was not… Continue

Added by Mike Pascoe on October 20, 2009 at 11:30am — No Comments

Surface EMG Decomposition & Dynamic Clamping


At 11:30 a.m. I attended a symposium titled "Decomposition of Surface EMG Signals into Constituent Action Potentials". This symposium consisted of an introductory presentation Dr. Carlo J. De Luca covering the physiology of surface EMG and the motor unit action potentials that comprise this signal. Following that the microphone was handed over the Dr. Hamid Nawab who discussed further the technical aspects of the decomposition algorithms that analyze the surface… Continue

Added by Mike Pascoe on October 19, 2009 at 9:30pm — No Comments

Variability in Measures of Hand Movements

Greater amount of visual feedback alters muscle activity and reduces force variability during constant isometric contractions.- 354.1

My Monday morning began with a stroll down the poster aisles, stopping first at the poster of Sim Baweja. The relation between visual feedback and force variability is unknown. Some have suggested that either too much or too little feedback can have a negative impact on force control (U-shaped function). Sim had subjects match a force target on… Continue

Added by Mike Pascoe on October 19, 2009 at 2:30pm — 1 Comment

Tendon Tap Responses in Stroke Patients.

Heteronymous Ia afferent connections in the upper limb following stroke- 271.4

My favorite poster of the Sunday afternoon session was discovered by pure chance. I was walking through the Theme D posters when the first word of the poster title "Heteronymous" caught my eye. Although I've done some work on heteronymous reflex modulation in healthy adults, I never knew what happened to these pathways with stroke. Thanks to Gwyn Lewis, I have a better idea : )

Gwyn's… Continue

Added by Mike Pascoe on October 18, 2009 at 6:30pm — No Comments

Fatigue in Neck Muscles & Trapezius Activity During Rest

The velocity recovery function in sternocleidomastoid muscle fibers and its dependence on fatigue- 179.22

My poster presentation was during Sunday morning's session. I don't typically stray very far from my own poser during the time it is up but I was able to review the work of a few posters in my area. Immediately next to me was a poster by Dr. Deborah Falla. Dr. Falla sought to investigate how muscle fatigue would alter the velocity recovery function of sternocleidomastoid… Continue

Added by Mike Pascoe on October 18, 2009 at 1:00pm — No Comments

Becoming Batman and Backyard Brains

Saturday afternoon was the official start of the poster presentations and a reminder of how massive this conference is.

Backyard brains: You too can do neurophysiology in your garage- # 20.1

"What would you say if I told you that you could record neuronal spikes for under $100?" As soon as I heard this I knew I was in the presence of Tim Marzullo, co-founder of Backyard Brains. Last year was… Continue

Added by Mike Pascoe on October 17, 2009 at 9:30pm — No Comments

Magic, the Brain, and the Mind - Synopsis

Presidential Welcome

This Dialogue began with a welcome to the conference by the President of SfN, Tom Carew. Highlights of this years' conference made by Tom include:

- First time held in Chicago

- 29,009 attendees as of this morning

- 40,000 members of the society as of last week

- 500 of the original 1,100 charter members… Continue

Added by Mike Pascoe on October 17, 2009 at 1:48pm — No Comments

Magic, the Brain, and the Mind

Well I got to the convention center this morning to discovered why I have nothing in my itinerary planner for this morning, nothing is happening yet!

I am set up in the special lecture area waiting for the Dialogues Between Neuroscience and Society to begin at 11 am.

My favorite twitter comment on this event is "I wonder if there will be an interlude of magic by Penn and Teller"!

A report is soon to follow :… Continue

Added by Mike Pascoe on October 17, 2009 at 11:35am — No Comments

SfN 2.0

Wow. I am amazed at the torrent of information about SfN on twitter at the moment. Not quite a "trending topic" (such as #ballonboy, happening just up the highway from Boulder), but definitely some new tweets to read after every refresh.

This made me realize that SfN has clearly entered a "2.0 stage". By this I mean that neuroscientists are now… Continue

Added by Mike Pascoe on October 16, 2009 at 1:47am — No Comments

Meet your NeuroBlogger

Hello, my name is Mike Pascoe and I am very excited to be blogging from SfN Chicago! You're probably asking yourself - who is this guy?

I am a PhD student in the Department of Integrative Physiology at the University of Colorado at Boulder. I work in the… Continue

Added by Mike Pascoe on October 14, 2009 at 10:30pm — No Comments

Best Poster Ever...

Hopefully at this point (4 days to go) you have made a good dent in the process of creating your Neuroscience poster.

For seasoned veterans, this is an easy task, completed in only a few hours. For others, merely deciding which software to use can delay typing that first word.

I've made my fare share of posters and in 2007 my lab-mates asked me to offer my suggestions on creating a great conference poster. Using the… Continue

Added by Mike Pascoe on October 12, 2009 at 12:30pm — No Comments

Optimizing SfN Poster Design Using Eye Tracking Software

For those preparing a poster presentation for this years' SfN, have a look at the following post I prepared from SfN 2008:


I wonder if the vendor will incorporate this as a demo at this years' conference?

- Mike

Added by Mike Pascoe on August 25, 2009 at 1:00pm — No Comments

Coverage of SfN 2009 Chicago

This October (16-21) I will be attending my 3rd Society for Neuroscience Meeting. The previous two meetings (2006 Atlanta, 2008 Washington DC) were excellent experiences and I am very much looking forward to Chicago.

My primary goal this year will be to network with lab PIs and identify a short list of labs I would like to post-doc in. I have a poster presentation on Sunday, Oct 18 from 8am-12pm, which is always a good opportunity to discuss my research with some of the best and… Continue

Added by Mike Pascoe on August 24, 2009 at 6:30pm — No Comments

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